Hacking Gut Cells to Produce Insulin – Diabetes 32

At previous post, we mentioned about possibility to produce insulin in the lab (petridish): Can Insulin be Produced from Laboratory Dish? - Diabetes 25 | Tanza Erlambang Update

Fig 01- A stray cat, just illustration

Now, scientists have developed a new method to produce insulin without “beta cells” from Pancreas. How?

The method is known as “hacking cells.” Researchers from Weill Cornell Medicine invented this method.

As reported by David Neil, published in ScienceAlert (2023: Scientists Hacked Human Cells to Make Insulin, And It Reversed Diabetes in Mice) that researchers to use stomach cell to replace roles of “beta cells.”

Why?

Fig 02- Painting by local artist, Brent

It is because both pancreatic and gut cells are close by during early development of human embryo, thus, not big deals to alter stomach steams to be like beta cells functions to produce insulin.

 Fig 03- Hibiscus flower, illustration

Sure, this is just early findings. Scientists might be need several steps further to apply to diabetes patients.

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