Could Available Drugs Regenerate beta Cells? – Part 2 - Diabetes 28

You may read previous posting (Part 1):

- Could Available Drugs Regenerate beta Cells? – Part 1 - Diabetes 28

Fig 01- Some drugs at pharmacy store

In addition to treat diabetes, GLP-1 receptor agonists (GLP-1 Ras) have other several advantages:

- heart health

- and kidney function

Researchers from Icahn medical school, Mount Sinai, New York combined both DYRK1A inhibitors and GLP-1 receptor agonists to see their effect on beta cell replication on human with diabetes.

The result is quite surprising!

Fig 02- A nice pet

Fig 03- Mermaid tail, illustration.

Finding of research may be summarized as following:

1) It is possible to replicate beta cells in diabetes patients

- previous research was fail.

2) Combine drugs able to produce beta cells in quite numbers

- about 5% to 6% after four days treatment.

- while using GLP-1 receptor agonist alone produce 2% beta cells only

3) Further developments

- Scientists believe that combines with other inhibitor drugs could increase cells replications significantly.

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